Aug 16, 2022
Late last month, the journal Science published an investigative
report that accused a much-cited publication in Alzheimer’s
disease... of fabricating scientific images. The study under
scrutiny was published in Nature in 2006 by Sylvain Lesné and
colleagues. It claimed that an amyloid oligomer called Aβ*56
impaired memory in mice. The recent Science report found potential
fabrication in the images used in that paper... and concluded that
this potential fabrication threatens the amyloid hypothesis in
Alzheimer’s disease. Here at ANA Investigates, we decided we needed
to ask the experts about that. Their conversation will help us
understand the impact of the recent investigative report on the
field of Alzheimer’s research. Series 3, Episode 10.
Featuring:
- Guest: Dr. Richard O’Brien, Alzheimer’s researcher, Chair of the
Department of Neurology at Duke University
- Interviewer/Producer: Dr. Erik Roberson, Alzheimer’s researcher,
endowed Professor of Neurology, and Director of the Alzheimer’s
Disease Center at the University of Alabama at Birmingham